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目的分析苯磺酸左旋氨氯地平片联合叶酸片及维生素B_(12)针治疗H型高血压的临床疗效。方法选取2015年1月-2015年9月单位老年病研究中心就诊的H型高血压患者164例,随机分为观察组与对照组各82例。观察组采用苯磺酸左旋氨氯地平片联合叶酸片及维生素B12针治疗,对照组给予苯磺酸左旋氨氯地平片治疗,对比2组疗效。结果治疗4周及8周后,观察组血压明显下降,下降幅度大于对照组,观察组治疗总有效率为91.46%,明显高于对照组74.39%,差异有统计学意义(P<0.05)。观察组治疗后血浆Hcy水平显著低于对照组(P<0.05)。结论采用苯磺酸左旋氨氯地平片联合叶酸片、维生素B_(12)针治疗H型高血压,疗效明显优于单独采用苯磺酸左旋氨氯地平片治疗,可有效降低患者血压及血浆Hcy水平,减少心脑血管事件的发生率。
Objective To analyze the clinical efficacy of levamlodipine besylate combined with folic acid tablets and vitamin B 12 in the treatment of Hypertension. Methods A total of 164 hypertensive Hypertensive patients admitted to the Unit of Geriatrics from January 2015 to September 2015 were randomly divided into observation group (n = 82) and control group (n = 82). The observation group was treated with levamlodipine besylate combined with folic acid tablets and vitamin B12 acupuncture. The control group was treated with levamlodipine besylate, which was compared with the two groups. Results After 4 weeks and 8 weeks of treatment, the blood pressure of the observation group decreased significantly (P <0.05). The total effective rate of the observation group was 91.46%, which was significantly higher than that of the control group (74.39%). Plasma Hcy levels in the observation group were significantly lower than those in the control group (P <0.05). Conclusions L-amlodipine besylate combined with folic acid tablets and vitamin B 12 needles is effective in treating Hypertension with L-amlodipine besylate alone, which can effectively reduce blood pressure and plasma Hcy Level, reduce the incidence of cardiovascular events.