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目的探讨青年肾病综合征与胆结石之间的相关因素。方法通过对208例青年肾病综合征患者常规胆系B型超声波检查，同时测定尿蛋白含量，血清胆固醇（TCH），甘油三酷（TG），低密度脂蛋白胆固醇（LDL－CH）。另选择同期年龄，性别相匹配体检者为对照组。结果208例肾病组患胆结石人数为30例，发生率14．4％，对照组124例患胆结石人数6例，发生率4．8％，两组相比有显著差异（P＜0．01）。结论青年肾病综合征患者蛋白尿，血清TCH、TG、LDL－CH浓度升高是胆结石发生的危险因素，应加强降脂抗凝治疗。
Objective To explore the correlation between young nephrotic syndrome and gallstones. Methods 208 cases of nephrotic syndrome in patients with conventional biliary ultrasound examination, simultaneous determination of urine protein, serum cholesterol (TCH), TG, LDL-LD. Another choice of the same age, gender-matched subjects for the control group. Results The incidence of gallstone in 208 cases of nephropathy group was 30 (14.4%). In control group, 124 cases of gallstone were found in 6 cases, the incidence was 4.8%. There was significant difference between the two groups (P <0. 01). Conclusion Proteinuria, serum TCH, TG, LDL-CH concentrations in patients with nephrotic syndrome are risk factors for gallstone development. Lipid-lowering anticoagulation therapy should be strengthened.