论文部分内容阅读
目的：探讨开展抗菌药专项整治活动对我院妇科Ⅱ类切口手术围手术期抗菌药使用情况的影响。方法：回顾性比较2011年4~9月(整治前)及2013年4~9月(整治后)妇科Ⅱ类切口手术抗菌药种类及用药频度( DDDs)、金额、用药时机、用量、疗程、联合用药情况。结果：整治后,总DDDs从1564.5降至419.3,抗菌药费用和总药品费用分别从(297.5±47.1)元、(806.4±63.1)元降至(108.3±29.6)元、(498.1±70.2)元,抗菌药构成比从(36.9±9.1)%降至(21.7±6.8)%,术后疗程从(3.7±1.4)d降至(1.5±0.6)d,差异均有统计学意义(P<0.05)；用药时机合理率、用量合理率、联合用药合理率分别从67.7%、81.5%、41.1%增至98.6%、100.0%和80.7%(P<0.05)。结论：开展抗菌药专项整治活动可明显提高我院妇科Ⅱ类切口手术围手术期抗菌药使用的合理性。“,”Objective:To explore the impact of special rectification on antibiotics application in the patients during perioperative period with gynecologic typeⅡincision in our hospital. Methods:The antibiotics type, use frequency, expense, administration time, dosage, treatment course and combined medication were retrospectively compared between April to September in 2011(before the recti-fication) and April to September in 2013 (after the rectification). Results: After the special rectification, the total DDDs was de-creased from 1 564. 5 to 419. 3, the expense for antibiotics and all drugs was respectively decreased from (297. 5 ± 47. 1) yuan to (108. 3 ± 29. 6) yuan and (806. 4 ± 63. 1)yuan to (498. 1 ± 70. 2) yuan, the proportion of antibiotics was decreased from (36. 9 ± 9.1) % to (21.7 ±6.8) %, and the treatment course was reduced from (3.7 ±1.4)d to (1.5 ±0.6)d(P<0.05). The rational rate of administration time, dosage and combined medication was respectively increased from 67. 7% to 98. 6%, 81. 5% to 100. 0%and 41. 1% to 80. 7%(P<0. 05). Conclusion:Special rectification can effectively improve the rational antibiotics use in gynecology department of our hospital during perioperative period of type Ⅱincision.