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目的探讨胃肠道间质瘤(GIST)的临床特征、诊断与治疗。方法回顾性分析1995年11月～2006年5月收治46例GIST的临床资料。结果术前行纤维胃肠镜、胃肠钡餐和B超等检查,确诊率低(4.4%)。全组均行手术治疗,切除率100%,其中根治性切除41例(89.1%),姑息性切除5例(10.9%),术后复发转移12例(26.1%),传统放疗和化学治疗效果甚微。结论术前确诊困难,确诊有赖于病理检查。手术切除是治疗的主要手段。
Objective To investigate the clinical features, diagnosis and treatment of gastrointestinal stromal tumors (GIST). Methods The clinical data of 46 patients with GIST from November 1995 to May 2006 were retrospectively analyzed. Results Preoperative examination of fiber gastrointestinal endoscopy, gastrointestinal barium meal and ultrasound B, the diagnosis was low (4.4%). Surgical treatment of the whole group were performed, the resection rate was 100%, of which radical excision in 41 cases (89.1%), palliative resection in 5 cases (10.9%), postoperative recurrence and metastasis in 12 cases (26.1%), conventional radiotherapy and chemotherapy Little. Conclusion Preoperative diagnosis is difficult and the diagnosis depends on the pathological examination. Surgical resection is the main treatment.