舒芬太尼以其对血流动力学干扰较轻,起效快,消除半衰期较短.镇痛效能更强的特点倍受临床医生的青睐,广泛应用于临床,尤其适用于心血管手术麻醉。现已证实预处理舒芬太尼可减轻心肌缺血再灌注损伤[1],对心肌有保护作用,但其对心肌细胞凋亡的影响却鲜有报道。本实验旨在通过检测大鼠心 Sufentanil with its haemodynamically less interference, rapid onset, shortened half-life to eliminate the more powerful analgesic characteristics of the clinician’s favor, widely used in clinical, especially for cardiovascular surgery anesthesia . It has been confirmed that sufentanil preconditioning can reduce myocardial ischemia-reperfusion injury [1], has a protective effect on myocardium, but its impact on myocardial cell apoptosis has been rarely reported. This experiment is designed to detect rat heart