作者报告应用表鬼臼毒素(VM-26)和阿搪胞苷联合治疗14例儿童急性白血病的结果。其中11例为急性淋巴细胞白血病(ALL),3例为细胞化学染色阴性的急性未分化细胞白血病。诊断时分类,5例属于标准危险白血病,9例为高度危险患者。14例中6例有早期中枢神经系统白血病,3例有纵膈肿块,5例系T细胞ALL。所有病例以往均经强的松、长春新碱、柔毛霉素治疗,13例还用了门冬酰胺酶,有的还加阿糖胞 The authors report the use of a combination of podophyllotoxin (VM-26) and acitretin for the treatment of 14 children with acute leukemia. Of these, 11 were acute lymphoblastic leukemia (ALL) and 3 were acutely undifferentiated cell leukemia with negative cytochemical staining. At the time of diagnosis, 5 cases belonged to standard risk leukemia and 9 cases were highly dangerous patients. Of the 14 patients, 6 had early stage central nervous system leukemia, 3 had mediastinal mass, and 5 had T cell ALL. All cases were treated with prednisone, vincristine, and daunorubicin in the past. 13 cases also used asparaginase, and some also added arabinose.