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目的通过检测非典型肺炎患者血清10项免疫指标,探讨其临床意义。方法采用金标法测定肺炎衣原体IgM和军团菌IgM,明胶凝集法测定肺炎支原体IgM,酶联免疫法测定腺病毒IgM、免疫比浊法测定免疫球蛋白IgG、IgA、IgM、补体C3、C4和C-反应蛋白。结果 68例非典型肺炎患者,肺炎衣原体IgM阳性率为7.35%;军团菌IgM阳性率为2.94%;腺病毒IgM阳性率为1.47%;肺炎支原体IgM漓度1:80-1:640阳性率为36.76%;C-反应蛋白阳性率为86.76%;IgA、IgM和C3均值明显高于正常人组。结论血清10项免疫指标的检测对非典型肺炎患者的诊治,具有一定的临床意义。
Objective To investigate the clinical significance of serum 10 immune markers in patients with atypical pneumonia. Methods Chlamydia pneumoniae IgM and Legionella pneumophila IgM were assayed by gold standard method, IgM of Mycoplasma pneumoniae was detected by gelatin agglutination method, IgM of adenovirus was detected by enzyme-linked immunosorbent assay, immunoglobulin IgG, IgA, IgM, complement C3, C4 and C-reactive protein. Results The positive rate of IgM in Chlamydia pneumoniae was 7.35% in 68 patients with atypical pneumonia, the positive rate of IgM in Legionella was 2.94%, the positive rate of IgM in adenovirus was 1.47%, the IgM in Mycoplasma pneumoniae was 1:80- The positive rate of 1: 640 was 36.76%. The positive rate of C-reactive protein was 86.76%. The mean values of IgA, IgM and C3 were significantly higher than those in normal subjects. Conclusion The detection of serum 10 immune indexes has certain clinical significance for the diagnosis and treatment of patients with atypical pneumonia.