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桃叶珊瑚苷在植物界中分布广泛,是玄参、杜仲、车前草等常用中药的有效成分之一,其药理作用也受到越来越多地关注,然而,桃叶珊瑚苷衍生物则鲜有报道。对桃叶珊瑚苷衍生物的结构类型(主要包括6-O取代型、10-O取代型、6,10-O双取代型、6′-O取代类型和其他类型)及近10年桃叶珊瑚苷及其衍生物的抗氧化、抗炎、抗菌、神经保护、抗肿瘤等药理活性进行综述。
Aucubin is widely distributed in the plant kingdom and is one of the active ingredients commonly used in traditional Chinese medicines such as Radix Scrophulariaceae, Eucommia ulmoides, Plantain and so on, and its pharmacological effects are also receiving more and more attention. However, aucubin derivatives Little report. The structural types of aucubin derivatives (including 6-O substituted, 10-O substituted, 6,10-O disubstituted, 6’-O substituted and other types) Auxiliary glycosides and derivatives of anti-oxidation, anti-inflammatory, antibacterial, neuroprotective, anti-tumor and other pharmacological activity are reviewed.