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目的:探讨2型糖尿病患者应用改良腹腔镜胃旁路术治疗的临床效果。方法:选取2013年2月至2015年3月就诊于广州新海医院的22例行改良胃旁路术治疗的2型糖尿病患者。22例患者均行改良腹腔镜胃旁路术。记录患者术前、术后的FPG、2 hPC、HbAlc、BMI、Fins的变化情况。结果:术后1个月患者的BMI、FPG、2 hPG水平与术前比较明显降低,术后3个月患者的HbAlc水平与术前比较出现明显降低,差异具有统计学意义(P<0.05);术后3、6、12个月患者的FPG、2 hPG水平降至正常;术后6、12个月患者的HbAlc水平降至正常;术后6、12个月患者的指数BMI趋于稳定,无显著变化;术后3个月患者的Fins水平明显高于术前差异具有统计学意义(P<0.05)。好转率18.18%,治愈率77.27%,总有效率为95.45%。结论:2型糖尿病患者在改良腹腔镜胃旁路术的治疗下取得了较好的临床疗效,患者的血糖水平得到有效的控制,且具有较高的安全性。
Objective: To investigate the clinical effect of modified laparoscopic gastric bypass in patients with type 2 diabetes mellitus. Methods: From February 2013 to March 2015, 22 patients with type 2 diabetes treated with modified gastric bypass were enrolled in Guangzhou Xinhai Hospital. Twenty-two patients underwent modified laparoscopic gastric bypass surgery. The changes of preoperative and postoperative FPG, 2 hPC, HbAlc, BMI and Fins were recorded. Results: The levels of BMI, FPG and 2 hPG were significantly decreased at 1 month after operation compared with that before operation. The levels of HbA1c at 3 months after operation were significantly lower than those before operation (P <0.05) ; The levels of FPG and 2 hPG decreased to normal at 3, 6 and 12 months postoperatively; HbA1c levels decreased to normal at 6 and 12 months postoperatively; and the index BMI of patients at 6 and 12 months postoperatively stabilized , There was no significant change. The level of Fins in patients at 3 months after operation was significantly higher than that before operation (P <0.05). Improvement rate of 18.18%, the cure rate of 77.27%, the total effective rate was 95.45%. Conclusion: Patients with type 2 diabetes mellitus have good clinical efficacy under the improved laparoscopic gastric bypass surgery. The patients’ blood glucose level is effectively controlled and has high safety.