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目的:探讨噬血细胞性淋巴组织细胞增生征的病因、临床特征及中西医结合治疗。方法:回顾性分析2008年4月—2010年9月确诊的9例HLH患者。结果:9例患者中有5例与感染相关,其中4例为EB病毒感染相关,4例为肿瘤相关,临床表现均符合HLH-2004诊断标准,本病属祖国医学温病中伏邪温病的范畴。经中西医结合治疗,存活4例,死亡5例。结论:HLH病因复杂,临床表现多样,病情凶险,死亡率高,及早诊断和中西医联合治疗可改善预后。
Objective: To investigate the etiopathogenisis, clinical features and the combination of traditional Chinese and western medicine in hemophagocytic lymphohistiocytosis. Methods: Nine patients with HLH diagnosed from April 2008 to September 2010 were retrospectively analyzed. Results: Of the 9 patients, 5 were related to infection, of which 4 were related to Epstein-Barr virus infection and 4 were tumor-related. Clinical manifestations were in line with the diagnostic criteria of HLH-2004. Category. After Integrative Medicine, survival in 4 cases, 5 deaths. Conclusion: The etiology of HLH is complex, with various clinical manifestations, dangerous condition and high mortality rate. Early diagnosis and combination of TCM and WM can improve the prognosis.