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IgA肾病(Berger氏病)以系膜IgA沉积为特征,伴有或不伴有C_2,IgM和IgG复合沉积,已报道系膜IgA沉积与上呼吸道或胃肠道感染以及肝硬化有关。患者常有血清IgA多聚体水平升高,有报道系膜型肾小球肾病患者通过循环淋巴细胞增加
IgA nephropathy (Berger’s disease) is characterized by the presence of mesangial IgA deposits with or without C 2, IgM and IgG complex deposition. It has been reported that mesangial IgA deposition is associated with upper respiratory or gastrointestinal infections and cirrhosis. Patients often have elevated serum IgA multimers, it has been reported in patients with mesangial glomerulonephritis by circulating lymphocytes increased