扎莫特罗(Xamoterol)是一种心脏选择性β_1-肾上腺素能受体部分激动剂,能有效地治疗体位性低血压。作者研究了5例shy-Drager综合征患者应用扎莫特罗的疗效,进一步观察这种疗效与主导的交感神经活性、β-肾上腺素能受体的敏感性和血压昼夜变化的联系。作者采用非侵袭性血压计(5200型,空间实验室制造)监测24小时血压。结果发现,5例Shy-Drager综合征患者静息状态血 Xamoterol, a cardiac selective beta-adrenergic receptor partial agonist, is effective in treating orthostatic hypotension. The authors studied the efficacy of zamothyroxide in 5 patients with shy-Drager syndrome and further investigated the association of this efficacy with predominant sympathetic activity, beta-adrenergic receptor sensitivity, and circadian blood pressure changes. The authors used a noninvasive sphygmomanometer (Model 5200, manufactured by Space Labs) to monitor 24-hour blood pressure. The results found that 5 cases of Shy-Drager syndrome in patients with resting blood