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硝普钠(Sodium nitroprusside,SNP)是现有处理高血压危象作用最迅速、疗效最可靠的药物。近年来,临床上也用于急性心肌梗塞与各种顽固性心力衰竭的治疗,获得良好效果。兹介绍如下。SNP 的药理SNP 是强力血管扩张剂,对静脉和小动脉平滑肌均有舒张作用,其作用的特异性很强,对胃肠道或子宫的平滑肌均无影响。其血管扩张作用与肾上腺素能受体或神经节无关,而是对血管平滑肌的直接作用。
Sodium nitroprusside (SNP) is the most effective and reliable drug to treat hypertensive crisis. In recent years, clinically used for the treatment of acute myocardial infarction and various refractory heart failure, and achieved good results. Here is the introduction. SNP pharmacological SNP is a potent vasodilator, venous and arteriolar smooth muscle relaxation, the role of specificity is very strong, no effect on the gastrointestinal tract or uterine smooth muscle. Its vasodilator effect has nothing to do with adrenergic receptors or ganglia, but a direct effect on vascular smooth muscle.