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目的：探讨肾毒性血清肾炎（ＮＳＮ）对大鼠左室心肌舒张性能的影响。方法：３０只ＳＤ大鼠随机分为Ａ、Ｂ和Ｃ组，每组１０只，，经静脉分别注射兔抗鼠肾毒血清、正常兔血清和生理盐水。注射后１４ｄ，做心导管检查。结果：Ａ组（ＮＳＮ组）左室－ｄｐ／ｄｔｍａｘ和等容舒张期左室内压下降时间常数分别与Ｂ、Ｃ组比较，均无显著性差异（Ｐ＞０．０５）。结论：ＮＳＮ不影响左室心肌舒张性能
Objective: To investigate the effect of nephrotoxic serum nephritis (NSN) on left ventricular diastolic function in rats. Methods: Thirty SD rats were randomly divided into A, B and C groups, with 10 rabbits in each group. Rabbit anti-rat nephrotoxic serum, normal rabbit serum and normal saline were injected intravenously. 14d after injection, do cardiac catheterization. Results: There was no significant difference in left ventricular-dp / dtmax in group A (NSN group) and left ventricular pressure descending time constant in isovolumic group compared with those in group B and C (P> 0.05). Conclusion: NSN does not affect left ventricular diastolic function