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本文报告了舌癌远处转移的研究,论述了血道扩散与转移的关系,提出了减少远处转移的方法。在188例舌癌患者中有10例远处转移的患者(5.3%,10/188);其中包括了7例肺转移及3例肝转移。肺转移为肝转移的2.3倍。此10例患者为鳞状上皮癌(8例),腺癌(1例),末分化癌(1例),分化程度皆为Ⅲ~Ⅳ级,说明清理分级与远处转移有重要关系。鳞状上皮癌老远处转移病例占80%(8/10);舌癌有远处转移同时存在预淋巴转移者占80%(8/10),说明远处转移与颈淋巴转移有密切关系。预防手术后远处转移的最好方法为施行手术前后的辅助化疗,以及施行术中局部区域性动脉灌注化疗。
This article reports the study on the distant metastasis of tongue cancer, discusses the relationship between the spread of bloodstream and metastasis, and proposes a method to reduce distant metastasis. Of the 188 patients with tongue cancer, 10 had distant metastases (5.3%, 10 of 188), including seven cases of lung metastases and three cases of liver metastases. Lung metastasis is 2.3 times that of liver metastasis. The 10 patients were squamous cell carcinoma (8 cases), adenocarcinoma (1 case) and end-differentiated carcinoma (1 case), all with grade Ⅲ ~ Ⅳ. It showed that there was an important relationship between the classification and distant metastasis. Squamous cell carcinoma distant metastasis cases accounted for 80% (8/10); tongue cancer distant metastasis with pre-lymphatic metastasis accounted for 80% (8/10), indicating distant metastasis and cervical lymph node metastasis are closely related . The best way to prevent distant metastasis after surgery is to administer adjuvant chemotherapy before and after surgery and to administer local regional arterial infusion chemotherapy.