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目的 探讨我国边境偏远地区新疆温泉县人间布鲁菌病(简称布病)流行与易感人群性别、年龄、职业以及病原种和生物型的相关性.方法 2014年,对温泉县既往发病率较高的7个乡、镇、场的1 148位牧工(203人)、兼牧农民(809人)和兽医(136人)进行虎红平板凝集试验初筛、试管凝集试验(SAT)确诊,采集急性期患者(未用抗生素治疗)全血12份,分离布鲁菌,将获得的疑似菌落纯化后进行进一步细菌学鉴定.结果 受试人群血清总体感染率为8.97％(103/1 148);感染率男性(11.91％,71/596)高于女性(5.80％,32/552),20 ～ 29岁年龄段的感染率最高(9.56％,13/136);布病感染的职业人群以牧民最高感染率为(10.34％,21/203),其次为农民(兼牧,感染率为8.65％,70/809);从急性期患者分离获得4份布鲁菌纯培养物,经鉴定均为羊种布鲁菌生物3型.结论 2014年温泉县流行菌株的生物型与我国布病总体流行一致,其布病疫情非常严峻,未来亟须加强政府指导下建立多部门参与的联防联控工作机制以有效遏制我国边境偏远地区布病的严峻形势.“,”Objective To explore the relationship between epidemic of human brucellosis and sex,age,occupation,Brucella species and biotypes of susceptible population in a Chinese remote border region,Wenquan County.Methods One thousand one hundred and forty-eight persons including 203 stockmen,809 pastoral farmers and 136 veterinarians were tested by Rose Bengal plate test and standard tube agglutination test of 2014 in a Chinese remote border region.Then the whole blood samples of 12 acute patients were used to isolate and identify Brucella wild strains.Results The positive rate of detected persons was 8.97％ (103/1 148).The positive rate of males (11.91％,71/596) was higher than that of females (5.80％,32/552).The population in the ages of 20-29years was the most susceptible (9.56％,13/136).The infectious rate of stockmen was the highest (10.34％,21/203),followed by pastoral farmers (8.65％,70/809).Four Brucella isolates were obtained from blood specimens and identified as Brucella melitensis biovar 3.Conclusions The epidemic situation of human brucellosis is very serious of 2014,in Wenquan County.The biovar of bacterial agent is consistent with the main biovar of overall China reported by Chinese Center for Disease Control and Prevention.In the future,more cooperation between multi-ministries should be strengthened under the guidance of government in order to effectively curb the grim situation of Chinese resource-poor border regions of brucellosis.