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Sertoli细胞亦称支持细胞或足细胞,是睾丸生精上皮中唯一的非生殖细胞。1865年该细胞首先为Sertoli所描述,并认为它是生精细胞的营养和支持细胞。1871年Ebher根据该细胞胞质包围连续的生殖细胞群以及同步发育的精子细胞嵌入其扩大的顶部胞质的现象,推测生殖细胞与Sertoli细胞之间存有某种依存关系。此后近一个世纪,Sertoli细胞并未引起人们更多的注意。近年来通过睾丸电子显微镜的研究和细胞培养技术的广泛应用,人们对Sertoli细胞的亚微结构和生理功能有了较清楚的了解,认识到该细胞与生精过程关系十分密切,干扰Sertoli细胞的生理功能将导致生精障碍。寻找选择
Sertoli cells, also known as supporting cells or podocytes, are the only non-germ cells in the testicular germinal epithelium. The cell was first described by Sertoli in 1865 and considered as a vegetative and supporting cell for spermatogenic cells. 1871 Ebher according to the cell cytoplasm surrounded by a continuous germ cell population and the simultaneous development of sperm cells embedded in its enlarged top of the cytoplasm of the germ speculated that there is a certain relationship between germ cells and Sertoli cells. For nearly a century, Sertoli cells did not attract more attention. In recent years, through the study of testicular electron microscope and the extensive application of cell culture technology, people have a clearer understanding of the submicroscopic structure and physiological functions of Sertoli cells, and recognize that the cells are closely related to the process of spermatogenesis and interfere with the process of Sertoli cells Physiological function will lead to spermatogenesis disorders. Find a choice