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选用40%乙烯利水剂作为染毒药物,大鼠急性经口采用霍恩氏法(Horn’s法),急性经皮采用最大限量法;家兔皮肤、眼刺激采用一次性眼、皮肤刺激试验;豚鼠致敏试验采用封闭式斑贴法。结果显示乙烯利对大鼠急性经口LD50雌雄性动物均为4300 mg/kg;对家兔眼具有腐蚀性,对家兔皮肤有强刺激性;对豚鼠致敏率为0。提示40%乙烯利水剂虽然对大鼠经口、经皮急性毒性为低毒,但因其呈酸性,对动物机体仍有一定的危害。
40% ethephon was used as the poisoning agent in rats. Horn’s method was adopted in acute oral administration in rats and the maximum percutaneous method was used in acute dermal administration. One-time eye and skin irritation test was used for skin and eye irritation in rabbits. Sensitization test using a closed patch method. The results showed that ethephon was 4300 mg / kg for acute oral LD50 in rats, corrosive to rabbits eyes and highly irritating to rabbit skin. The sensitization to guinea pigs was zero. Tip 40% ethephon Although oral toxicity of acute toxicity in rats is low toxicity, but because of its acidic nature of the body still has some dangers.