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目的探讨临床五种常用阴道洗剂对阴道分离菌的体外抗菌活性。方法根据使用说明书将五种洗剂用无菌蒸馏水稀释至使用浓度,用五种标准菌株及从临床阴道分泌物中分离的90株细菌采用牛津杯法进行体外药物敏感性试验。结果五种常用阴道洗剂的抗菌效果依次为甲硝唑氯己定洗液>利夫康乐洗剂>百艾洗剂>日舒安洗剂>洁尔阴洗剂。结论五种阴道洗剂均具有抗菌活性,以甲硝唑氯己定洗液最优。
Objective To investigate the in vitro antibacterial activity of five commonly used vaginal washes against vaginal bacteria. Methods Five lotions were diluted to sterile concentrations with sterile water according to the manufacturer’s instructions. The in vitro drug susceptibility test was conducted using the five standard strains and 90 strains isolated from clinical vaginal secretions using the Oxford cup method. Results The antibacterial effects of five commonly used vaginal lotion were as follows: Metronidazole chlorhexidine lotion> Liv-Kang Le lotion> Bai AI lotion> Risso-An lotion> Jie-er Yin lotion. Conclusions All five vaginal lotion agents have antimicrobial activity and metronidazole chlorhexidine lotion is the best.