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目的 :探索心脑血管病慢性肺炎衣原体 ( CP)感染的血清学证据。 方法 :采用 Micro- IF检测血清特异性CP抗体。 结果 :发现约 37%心脑血管病患者血清特异性 CP- Ig A抗体水平升高 ,与献血员组 ( 3% )比差异非常显著 ( P<0 .0 1) ;特异性 CP- Ig G、CP- Ig M抗体阳性率与献血员组无显著差异 ( P>0 .0 5 )。 结论 :CP特异性 Ig A抗体与 CP慢性感染相关 ,是慢性 CP感染的标记物 ,可应用于心脑血管病慢性 CP感染 (带毒 )者及相关疾病的研究与诊断
Objective: To explore the serological evidence of Chronic Chlamydia pneumoniae (CP) infection in cardio-cerebrovascular disease. Methods: Serum-specific CP antibodies were detected by Micro-IF. Results: Serum specific CP-Ig A antibody levels in about 37% of patients with cardiovascular and cerebrovascular diseases were found to be significantly higher than those in the blood donors (3%) (P <0.01). Specific CP-Ig G The positive rate of CP-Ig M antibody was not significantly different from that of donors (P> 0.05). CONCLUSION: CP-specific IgA antibody is associated with chronic infection of CP and is a marker of chronic CP infection. It can be used in the research and diagnosis of chronic CP infection (with poison) in cardiovascular and cerebrovascular diseases and related diseases