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近年来,端粒(telomere)与端粒酶(telomerase)的研究逐渐成为医学研究热点,早在20世纪80年代,人们对端粒和端粒酶已有较多的认识。1985年由Creider[1]从四膜虫的细胞提取物中首次发现端粒酶。1989年Morin首次在人的癌细胞中发现端粒酶。1994年Kim[2]首创高度敏感特异的PCR-TRAP?
In recent years, the study of telomere and telomerase has become a hot research topic in medicine. As early as the 1980s, telomere and telomerase have been widely recognized. Telomerase was first found in cell extracts of Tetrahymena by Creider [1] in 1985. Morin first discovered telomerase in human cancer cells in 1989. Kim [2] pioneered highly sensitive PCR-TRAP in 1994