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目的探讨心肌肌钙蛋白T(cTnT)在急性心肌梗死(AMI)早期诊断中的意义。方法采用电化学发光法测定健康对照组、AMI组血清中心肌肌钙蛋白T(cTnT)和肌酸激酶同工酶(CK-MB)水平并进行比较分析。结果 31例AMI患者就诊时cTnT和CK-MB阳性率分别为90%和48%,入院24h后阳性率分别为100%和87%。健康对照组的结果均在正常参考值范围内。结论对于AMI患者来说,cTnT的诊断敏感性、特异性优于传统项目CK-MB。
Objective To investigate the significance of cardiac troponin T (cTnT) in the early diagnosis of acute myocardial infarction (AMI). Methods The levels of cardiac troponin T (cTnT) and creatine kinase MB (CK-MB) in serum of healthy control group and AMI group were determined by electrochemiluminescence method and compared. Results The positive rates of cTnT and CK-MB were 90% and 48% respectively in 31 AMI patients and 100% and 87% respectively after 24h admission. The results of the healthy control group are within the normal reference range. Conclusion For patients with AMI, the diagnostic sensitivity and specificity of cTnT are better than those of traditional CK-MB.