近几年来,人们应用人血浆活性蛋白C(Activated Protein C,APC)作为抗凝剂,采用不同的动物模型,对其潜在的抗栓效应进行实验研究。在预防动脉阻塞和抑制血小板性血栓形成的动物实验中,凝血酶抑制因子所起的作用从反面提示了凝血酶在血栓形成的病因中起重要作用,凝血酶的活性是由循环血中自然产生的抑制因子的量来调控的,特别是 In recent years, people use human activated protein C (Activated Protein C, APC) as anticoagulants, using different animal models, its potential antithrombotic effect of experimental study. In animal experiments to prevent arterial occlusion and inhibit platelet thrombosis, the role of thrombin inhibitors suggests that thrombin plays an important role in the etiology of thrombosis and that thrombin activity is naturally produced by circulating blood The amount of inhibitory factor to regulate, in particular