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目的评估代谢肿瘤体积(MTV)对非小细胞肺癌患者术后的复发预测情况。方法回顾性分析112例行完全性切除术的非小细胞肺癌患者,术前均行18F-FDG PET/CT检查,术后进行追踪随访。应用ROC曲线分析MTV对复发的预测性能。应用Cox比例风险回归模型进行多因素分析探讨复发与相关危险因素之间的关系。结果 ROC曲线比较表明,MTV2.5较SUV max有更好的预测复发的性能。MTV2.5较小的患者具有更高的无复发生存率。多因素分析显示MTV2.5和TNM分期是影响复发的独立危险因素。结论 MTV是判断非小细胞肺癌术后复发的重要预后因素。
Objective To assess the predictive value of metabolic tumor volume (MTV) for postoperative recurrence in patients with non-small cell lung cancer. Methods A total of 112 patients with non-small cell lung cancer who underwent complete resection were retrospectively analyzed. All patients underwent 18F-FDG PET / CT preoperatively and were followed up. The ROC curve was used to analyze the predictive performance of MTV on recurrence. Cox proportional hazards regression model was used for multivariate analysis to explore the relationship between relapse and related risk factors. Results ROC curve comparison showed that MTV2.5 better predict the recurrence performance than SUV max. Patients with smaller MTV2.5 have a higher recurrence-free survival rate. Multivariate analysis showed that MTV2.5 and TNM staging were independent risk factors of recurrence. Conclusions MTV is an important prognostic factor in determining postoperative recurrence of non-small cell lung cancer.