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目的探讨有创机械通气治疗肾移植术后重症肺部感染合并急性呼吸衰竭的机械通气时机对预后的影响。方法收集67例肾移植术后重症肺部感染合并急性呼吸衰竭并接受气管插管、呼吸机辅助呼吸的患者的临床资料,分为早期组(39例)与晚期组(28例)上机组,比较两组血气参数、呼吸频率(f)、氧合指数(PaO2/FiO2)、MODS、带机时间及并发症,两组间差异有统计学意义(P<0.05)。结果与结论肾移植术后重症肺部感染合并急性呼吸衰竭的患者的预后受多种因素影响,把握最佳机械通气治疗的时机仍是最关键的环节,当患者的低氧血症对增加吸入氧浓度反应不佳时,即应考虑行呼吸机辅助通气。
Objective To investigate the effect of mechanical ventilation on the prognosis of patients with severe pulmonary infection and acute respiratory failure after renal transplantation. Methods The clinical data of 67 patients with severe pulmonary infection complicated with acute respiratory failure after renal transplantation and receiving endotracheal intubation and ventilator assisted breathing were collected and divided into early stage (39 cases) and late stage (28 cases) Blood gas parameters, respiratory rate (f), oxygenation index (PaO2 / FiO2), MODS, and the time and complications of the two groups were compared. There was significant difference between the two groups (P <0.05). RESULTS AND CONCLUSION: The prognosis of patients with severe pulmonary infection and acute respiratory failure after kidney transplantation is affected by many factors. It is still the most crucial step to grasp the timing of the optimal mechanical ventilation. When patients’ hypoxemia increases their inhalation Oxygen concentration of poor response, which should consider the ventilator assisted ventilation.