淋巴系统是人类恶性肿瘤的主要转移途径,几乎所有的肿瘤在局限期时,淋巴结转移是非常重要的不良预后因素。一些动物模型发现,抑制区域性淋巴结转移可以减少远处转移,因此推测肿瘤远处器官的转移需要经过淋巴结。过去认为,肿瘤细胞淋巴道转移是经过肿瘤周围已经存在的淋巴 Lymphatic system is the main metastasis of human malignant tumor. In almost all tumors, lymph node metastasis is a very important adverse prognostic factor in the limited period. Some animal models found that inhibition of regional lymph node metastasis can reduce the distant metastasis, so speculated that distant metastasis of tumor need to pass through the lymph nodes. In the past that the tumor cell lymphatic metastasis is through the tumor has been around the lymph