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目的 在接受机械通气的新生儿中进行早期微量喂养 ,观察其对新生儿胃肠道动力的影响。方法 收集 1998年 9月至 1999年 2月间 ,机械通气的 13例患儿 ,分早期喂养组 (6例 )和常规喂养组 (7例 )。早期微量喂养组平均在生后 2 .5d开始开奶 (每 2小时 2ml/kg) ,常规喂养组为生后13 .6d ,两组均在生后第 3天开始静脉营养。当两组患儿病情稳定后 ,进行放射性核素胃食管显像和血胃泌素、胃动素测定。结果 早期微量喂养组的胃排空率 (32 .6± 12 .2 ) %快于常规喂养组 (16 .0± 5 .5 ) %、到达全量肠内营养时间为 (17.5± 8.0 )d对 (34.9± 17.7)d以及拔胃管时间 (12 .2± 8.3)d对 (31± 11.2 )d均明显缩短 (P <0 .0 5 ) ,但两组在反流指数、血胃泌素、胃动素水平、恢复出生体重时间以及住院天数等方面差异不明显。结论 早期微量喂养能促进胃肠动力成熟 ,缩短到达全量肠内营养的时间并早日建立经口喂养 ,减少喂养困难的发生。
Objective To investigate the effect of early micronutrients on neonatal gastrointestinal motility in neonates undergoing mechanical ventilation. Methods Thirteen children undergoing mechanical ventilation were enrolled in this study from September 1998 to February 1999, divided into two groups: the early feeding group (6 cases) and the routine feeding group (7 cases). In the early micronutrition group, the average milk volume was started at 2.5 days after birth (2ml / kg every 2 hours), and the routine feeding group was 13.6 days after birth. Both groups started intravenous nutrition on the 3rd day after birth. When the two groups of children with stable disease, radionuclide gastroesophageal imaging and blood gastrin, motilin determination. Results The rate of gastric emptying (32.6 ± 12.2%) in early micronutrition group was faster than that of routine feeding group (16.0 ± 5.5%), and the total enteral nutrition time was (17.5 ± 8.0) d (34.9 ± 17.7) days and gastric tube extubation time (12.2 ± 8.3) d (31 ± 11.2) days were significantly shorter (P <0.05), but the two groups in the reflux index, blood gastrin , Motilin levels, birth weight recovery time and hospital days and other aspects of the difference is not obvious. Conclusion Early micronutrient feeding can promote gastrointestinal motility maturity, shorten the time to reach the full amount of enteral nutrition and establish oral feeding as soon as possible to reduce the occurrence of feeding difficulties.