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目的研究心理干预对肺结核抑郁情绪患者临床治疗效果的影响,为伴抑郁情绪的肺结核患者的有效治疗提供方法。方法选择2008年1月至2013年8月在我院结核科住院及门诊治疗的85例肺结核抑郁情绪患者作为研究对象,随机分为干预组(42例)和对照组(43例)。对照组给予抗痨药物治疗,干预组在此基础上进行心理干预。治疗后观察患者痰菌阴转情况,动态观察肺部影像变化,应用Zung抑郁自评量表(SDS)进行SDS评分,并综合评价疗效。结果抗痨6个月时,干预组痰菌阴转率为97.4%,空洞闭合率为58.6%,总有效率为92.9%,均显著高于对照组(分别为76.3%、32.1%和59.5%),差异均有统计学意义(P<0.05)。治疗前,两组SDS评分比较,差异无统计学意义(P>0.05)。在心理干预治疗后第2、4和6个月,干预组SDS总分均低于对照组,差异均有统计学意义(P<0.05)。结论对肺结核抑郁情绪患者在进行躯体疾病治疗的同时进行心理干预,可以取得更好的临床疗效。
Objective To study the effect of psychological intervention on clinical treatment of patients with pulmonary tuberculosis depression and provide a method for the effective treatment of pulmonary tuberculosis patients with depression. Methods From January 2008 to August 2013, 85 patients with tuberculosis and depression in our inpatient and outpatient department of tuberculosis in our hospital were randomly divided into intervention group (n = 42) and control group (n = 43). The control group was treated with anti-tuberculosis drugs, intervention group on the basis of psychological intervention. After treatment, the patient’s sputum negative conversion was observed, the lung image was dynamically observed, and the SDS score of Zung depression self-rating scale (SDS) was used to evaluate the curative effect. Results At 6 months, the negative conversion rate of sputum in the intervention group was 97.4%, the void closure rate was 58.6% and the total effective rate was 92.9%, which were significantly higher than those in the control group (76.3%, 32.1% and 59.5% respectively) ), The differences were statistically significant (P <0.05). Before treatment, there was no significant difference in SDS scores between the two groups (P> 0.05). At the 2nd, 4th, and 6th month after psychological intervention, the SDS scores in the intervention group were all lower than those in the control group, with significant differences (P <0.05). Conclusions Psychological interventions for patients with tuberculosis of depression in the treatment of somatic diseases can achieve better clinical efficacy.