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我院制剂室在生产制备乳酸环丙沙星注射液过程中,为了提高注射液的澄明度和吸附然原,按《药局技术操作手册》规定加入0.05%~0.1%活性炭,在含量测定时发现成品中环丙沙星含量明显低于投料量。为了探讨环丙沙星含量下降的原因,特做如下实验,供制剂生产参考。1实验方法与结
In our hospital preparation room in the process of preparation of ciprofloxacin lactate injection, in order to improve the clarity of the injection and absorption of the original, according to the “Pharmacy Technical Manual” by adding 0.05% to 0.1% activated carbon, In the determination of content found in the finished product ciprofloxacin content was significantly lower than the amount of feed. In order to explore the reasons for the decline of ciprofloxacin, special make the following experiments for the preparation of production reference. 1 Experimental Methods and Results