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目的评价1981～2004年卡介苗接种质量,考核免疫效果。判断卡介苗接种对儿童结核病流行趋势的影响,落实“十一五”结核病控制规划,有效保护儿童身体健康。方法对1981～2004年卡介苗接种统计表和儿童结核病档案资料归纳统计对比分析。结果新生儿卡介苗接种率、卡痕率、阳转率均呈逐年上升趋势。儿童结核性脑膜炎发病率呈逐年下降趋势。儿童结核病发病率呈持续徘徊状态,可能与各医疗单位对儿童结核病疫情漏报或未转诊结防机构有关,有待研究。结论卡介苗形成有效的免疫屏障,充分肯定了卡苗的免疫效果。
Objective To evaluate the quality of BCG vaccination from 1981 to 2004 and evaluate the immune effect. Determine the impact of BCG vaccination on the prevalence of tuberculosis in children and implement the “Eleventh Five-Year” TB Control Plan to effectively protect children’s health. Methods A comparative analysis of statistical records of BCG vaccination statistics and childhood tuberculosis records from 1981 to 2004. Results Neonatal BCG vaccination rate, card rate, positive rate showed a rising trend year by year. The incidence of tuberculosis in children showed a decreasing trend year by year. The incidence of tuberculosis in children continues to hovering state, which may be related to various medical units of omission of tuberculosis in children or non-referral of anti-tuberculosis institutions, to be studied. Conclusion BCG formed an effective immune barrier, which fully affirmed the vaccine’s immune effect.