观察了单甘酯 ( Glycol Mannate Sulfate,GMS)对血小板聚集、粘附功能及小鼠尾出血时间的影响。结果表明单甘酯 2 5,50 mg· kg-1剂量组对血小板粘附有显著抑制作用 ,P<0 .0 1;2 5,50 ,10 0 mg· kg-1能明显抑制胶原和花生四烯酸诱导的血小板聚集 ,对 ADP诱导的血小板聚集无抑制作用。单甘酯 4 0 ,80 mg· kg-1可明显延长小鼠尾出血时间。结果证明单甘酯有明显的抗血小板作用 The effects of Glycol Mannate Sulfate (GMS) on platelet aggregation, adhesion and tail bleeding time were observed. The results showed that monoglyceride 25,50 mg · kg-1 dose group on platelet adhesion was significantly inhibited, P <0.01; 25,50,50,10 mg · kg-1 can significantly inhibit collagen and peanut Tetraenoic acid-induced platelet aggregation has no inhibitory effect on ADP-induced platelet aggregation. Monoglycerides 40, 80 mg · kg-1 can significantly prolong the mouse tail bleeding time. The results show that monoglycerides have obvious anti-platelet effect