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我们曾报告了消旋17-苯-18,19,20-失三碳PGF_2a甲酯(lA)及其15-差向异构体(1B)的合成[1]、[1A)对小鼠抗生育活性已大大超过其母体化合物PGF_2α,与15-甲基PGF_2a甲酯(IC)不相上下[2]。[1A]与(1A)与(1C)不
We have reported the synthesis of rac-17-Benzene-18, 19,20-tri-PGF2a methyl ester (lA) and its 15- epimer (1B) Fertility activity has greatly exceeded its parent compound PGF 2α, and 15-methyl PGF_2a methyl ester (IC) comparable [2]. [1A] Unlike (1A) and (1C) No