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手足口病(Hand foot and mouth diease,HFMD)是由肠道病毒引起的一种儿童常见传染病。大多数患者症状轻微,以发热和手、足、口腔等部位的皮疹或疱疹为主要特征。少数患者可并发无菌性脑膜炎、脑炎、急性弛缓性麻痹、呼吸道感染和心肌炎等。该病的病原体主要为柯萨奇病毒A组的16、2、4、5、7、9和11型,柯萨奇病毒B组的1、2、3、4、5和13型,部分埃可病毒和肠道病毒71型。最常见的为柯萨奇病毒A 16型(Cox A16)和肠道病毒71型(EV 71)[1]。
Hand foot and mouth diease (HFMD) is a common childhood infectious disease caused by enteroviruses. Most patients with mild symptoms, with fever and hand, foot, mouth and other parts of the rash or herpes as the main feature. A small number of patients may be complicated by aseptic meningitis, encephalitis, acute flaccid paralysis, respiratory infections and myocarditis. The pathogens of this disease are mainly Coxsackievirus A, types 16, 2, 4, 5, 7, 9 and 11, Coxsackievirus B, types 1,2,3,4, 5 and 13, Can be virus and enterovirus 71 type. The most common Coxsackie A16 (Cox A16) and enterovirus 71 (EV 71) [1].