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春季结膜炎是变态反应性眼病,以往采用激素治疗,疗效不够理想,且易发生副作用。Abelson等认为:花生四烯酸的代谢产物前列腺素是变态反应炎症中的介质之一,本病患者的眼充血、水肿、粘性分泌物和嗜酸性细胞趋化性是前列腺素D_2所引起,阿司匹林通过阻断环氧酶途径阻止前列腺素D_2的生物合成而生产抗炎作用。该氏等于1983年首次报告应用阿司匹林治疗本病患者3例,取得较好疗效。国内也有应用阿司匹林、消炎痛治疗本病的报道,我们在临床应用中体会到上述药品虽有一定药效,但副作用较多,不适于较长时间服用,自1985
Spring conjunctivitis is allergic eye disease, hormone therapy in the past, the effect is not ideal, and prone to side effects. Abelson and other that: the metabolite of arachidonic acid prostaglandin is one of the media of allergic inflammation, the patient’s eye congestion, edema, viscous secretions and eosinophil chemotaxis is caused by prostaglandin D_2, aspirin Anti-inflammatory effects are produced by blocking the cyclooxygenase pathway from blocking the biosynthesis of prostaglandin D_2. The equivalent of 1983, the first reported application of aspirin in patients with this disease in 3 cases, and achieved good results. There are also domestic application of aspirin, indomethacin treatment of the disease reports, we appreciate the clinical application of these drugs, although some efficacy, but more side effects, not suitable for a longer time to take, since 1985