本文通过对健康不吸烟组,无症状吸烟组及慢性支气管炎组的肺功能测定,发现长期持续吸烟可导致阻塞性通气功能障碍。在FEV1.0%、MMEF及FEF75～85%的3项指标测定中,MMEF敏感性最高。目前MEFV尚不能广泛应用之前,MMEF在筛选小气道病变中是一项值得推行的简便易行的方法。 In this paper, the lung function of healthy non-smoking group, asymptomatic smoking group and chronic bronchitis group were determined. It was found that persistent smoking could lead to obstructive ventilatory dysfunction. In FEV1.0%, MMEF and FEF75 ~ 85% of the three indicators measured, MMEF the highest sensitivity. Until now MEFV is not yet widely available, MMEF is a simple and easy method to screen for small airway disease.