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为探索母乳对婴儿肠道微生态与迟发型母乳性黄疸(LBMJ)的影响,随机选择出生后(26±2)天仍有明显黄疸的母乳喂养儿、健康无黄疸母乳喂养儿及配方乳喂养儿各15例,留取出生后第28天24小时粪便,检测肠道菌群及粪胆原含量。结果显示母乳喂养儿肠道中大肠杆菌和梭菌的建立较配方乳喂养儿明显延迟(P<0.05),粪中粪胆原含量配方乳喂养儿明显高于母乳喂养黄疸儿(P<0.005)。提示转化胆红素成粪胆原的肠道菌群建立延迟,可能是LBMJ发生的重要原因之一。
In order to explore the effect of breast milk on intestinal microflora and late-onset breast milk jaundice (LBMJ) in infants, we randomly selected breastfeeding children with jaundice at birth (26 ± 2) days, healthy jaundice-free breastfeeding and formula feeding Fifteen children were enrolled, and the faeces were collected 24 hours after birth on the 28th day to detect the intestinal flora and the content of fecal bile. The results showed that the establishment of Escherichia coli and Clostridium in breastfeeding children’s intestine was significantly delayed than that of formula-fed children (P <0.05). Fecal creatinine content in formula fed milk was significantly higher than that of breast-fed jaundice (P <0.005). Suggesting that the conversion of bilirubic into fecal protracted intestinal flora delay may be one of the important reasons for the occurrence of LBMJ.