流脑A群多糖菌苗最佳免疫程序研究

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本文通过对流脑菌苗三个不同程序组的免疫效果研究,结果表明:对16个月至1岁半的婴幼儿初种一针,次年复种一针,其免疫效果和工作实施的可行性均优于国内资料报道的初种后间隔三个月复种的结果此程序对处于流脑散发年或低发的地区控制流脑发生与流行有一定实用价值但是婴纪儿完成两针免疫后三年,其血清抗体已有明显下降趋势,为了保证大龄儿童免患流脑,根据对三针组和五针组免疫效果研究结果。我们认为,对我省及其他一些流脑高发地区,在控制流脑流行当中,要达到既经济有效,又切实可行的目的,每年除对婴幼儿做好两针免疫外,另应对当年7岁儿童复种一针,并建议,在流脑高发地区,可将此程序纳入计划免疫 In this paper, the immunization effect of three different program groups of meningococcal vaccine was studied. The results showed that the immunization effect and the feasibility of the implementation of one needle for infants and young children from 16 months to 1 year old and one needle for the next year Are better than the domestic data reported after the initial interval of three months of multiple crop results This program is in the meridian or low incidence of regional control of meningitis occurrence and epidemic have some practical value However, Year, the serum antibody has a significant downward trend, in order to ensure that older children from suffering from meningitis, according to the three-needle group and the five-needle group immune effect study results. In our opinion, in our province and other areas with high incidence of meningitis, in controlling the epidemic of meningitis, it is necessary to achieve both economic and practical purposes. In addition to the two-dose immunization to infants and young children, we should also deal with the problem of the seven-year-old Children are given a second vaccination and suggest that this procedure be included in the planned immunization in meningitis areas
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