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[目的]观察双歧杆菌四联活菌素片联合白术芍药散加味治疗肠易激综合征(IBS)的疗效。[方法]IBS患者121例,随机分为2组,治疗组62例,予双歧杆菌四联活菌素片口服,每次3片,每日3次;白术芍药散加味每日1剂(60ml)。对照组59例,单用双歧杆菌四联活菌素片,每次3片,每日3次,治疗2、4周后,2组进行疗效比较。[结果]治疗2周后,治疗组总有效率85.5%,对照组78.0%(P<0.05);治疗4周后,治疗组总有效率98.4%,对照组86.4%(P<0.01),2组患者均未发现明显的不良反应。[结论]双歧杆菌四联活菌素片联合白术芍药散加味治疗IBS有较好的疗效,值得临床应用。
[Objective] To observe the curative effect of bifidobacterium quadricepsin combined with Baizhu Shaoyao San on the treatment of irritable bowel syndrome (IBS). [Method] 121 patients with IBS were randomly divided into two groups, the treatment group of 62 cases, Bifidobacterium quadricepsin tablet orally, each 3 tablets, 3 times a day; Baizhu Shaoyao San flavored daily 1 dose 60ml). The control group of 59 cases, single Bifidobacterium quadruple antibiotic tablets, each 3, 3 times a day, after 2,4 weeks of treatment, the two groups were compared. [Results] After 2 weeks of treatment, the total effective rate was 85.5% in the treatment group and 78.0% in the control group (P <0.05). After 4 weeks of treatment, the total effective rate was 98.4% in the treatment group and 86.4% in the control group (P <0.01) No significant adverse reactions were found in the patients. [Conclusion] Bifidobacterium quadricepsin combined with Baizhu Shaoyao San flavored treatment of IBS has a good effect, it is worth clinical application.