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目的观察米索前列醇对晚期妊娠引产的可行性、有效性和安全性。方法选择有引产指证、无引产及米索前列醇使用禁忌证的单胎、头位、胎膜完整的晚期妊娠妇女140例,随机分为A、B两组,其中米索组80例,催产素组60例。对两组引产时效、母儿并发症的发病情况作分析比较。结果米索组较催产素组可明显改善子宫颈评分,缩短引产至分娩时间(P<0.01～P<0.001),两组母儿并发症差异均无统计学意义(P>0.05)。结论米索前列醇用于晚期妊娠引产安全有效,可缩短产程。
Objective To observe the feasibility, efficacy and safety of misoprostol in induction of labor during late pregnancy. Methods One hundred and seventy pregnant women with single fetus, head position and complete fetal membranes without induced abortion and misoprostol use were randomly divided into A and B groups, including 80 cases of misoprostol, Supramolecular group of 60 cases. The two groups of induction of labor, maternal and child complications of the incidence for the analysis and comparison. Results Compared with oxytocin group, the misoprostol group significantly improved the cervical score and shortened the time between induction and delivery (P <0.01 ~ P <0.001). There was no significant difference in the complications between the two groups (P> 0.05). Conclusion Misoprostol is safe and effective for induction of labor in late pregnancy, which can shorten the labor process.