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局部麻醉药中只有普鲁卡因是一种可能的致畸原(见附表)。在某个研究中,对许多大鼠可引起白内障,但在另一些实验中却出现了阴性的结果。有些全身麻醉药对啮齿动物有致畸胎的作用。
Only procaine is a possible teratogen in local anesthetics (see attached table). In one study, cataracts were found in many rats but negative in others. Some general anesthetics have teratogenic effects on rodents.