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目的分析某院2015年595例围术期患者抗菌药物临床使用的合理性以及不合理用药及其对策。方法通过单纯随机抽样,抽取2015年1—12月进行手术治疗患者病历595份,采用回顾性分析,评价围术期预防使用抗菌药物的合理性。结果 595份病历中,围术期用药病历390份(65.55%),其中不合理预防使用的原因主要有无适应证用药(4.62%)、药物选择不合理(42.05%)、用药时机不合理(17.44%)、用法用量不合理(14.87%)、用药疗程不合理(59.49%)和术中追加不合理(0.77%)。结论在抗菌药物专项整治以来围术期抗菌药物使用日趋合理,但仍存在一些显著问题,应加强监督和管理,重视临床药学,规范用药行为,促进合理用药,提高医疗质量。
Objective To analyze the rationality of clinical use of 595 perioperative antibiotics in a hospital in 2015 and its unreasonable use of drugs and its countermeasures. Methods By means of simple random sampling, 595 cases of patients undergoing surgical treatment from January to December in 2015 were retrospectively analyzed to evaluate the rationality of perioperative prevention of antibacterials. Results Among the 595 medical records, perioperative medical record was 390 (65.55%), of which, the reason for the unreasonable prevention was mainly the presence or absence of indications (4.62%), the unreasonable choice of drugs (42.05%), the timing of medication was unreasonable 17.44%). The dosage was unreasonable (14.87%), medication was irrational (59.49%) and intraoperative unreasonable (0.77%). Conclusion Perioperative use of antimicrobial agents has become more and more reasonable since the special rectification of antimicrobial agents. However, there are still some significant problems. Supervision and management should be strengthened, clinical pharmacy should be emphasized, drug use should be standardized, drug use should be promoted, and quality of medical care should be improved.