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δ抗原首先由意大利学者Rizzetto,于1977年在慢性乙型肝炎患者的肝细胞核中发现,以后又发现这种抗原为内含δ基因组和δ抗原,外被HBsAg的杂交
The δ antigen was first discovered by the Italian scholar Rizzetto in the hepatocyte nucleus of patients with chronic hepatitis B in 1977 and later found to contain the δ genome and δ antigen and was hybridized with HBsAg