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1概述心血管疾病是慢性肾脏病(chronic kidney disease,CKD)患者致残和致死的主要原因,超过50%尿毒症(CKD-V期)患者死于心血管疾病,其风险比普通人群高出20~30倍。近年来的研究提示骨及矿物质代谢紊乱有可能是通过动脉血管钙化的机制而导致心血管疾病的发生和发展,最终影响CKD患者的生存率,目前这个问题已受到越来越多
1 Overview Cardiovascular disease is a major cause of disability and death in patients with chronic kidney disease (CKD). More than 50% of patients with uremia (CKD-V) die of cardiovascular disease and have a higher risk than the general population 20 to 30 times. In recent years, studies suggest that bone and mineral metabolism disorders may be caused by the mechanism of arterial calcification and the occurrence and development of cardiovascular disease, and ultimately affect the survival rate of patients with CKD, the problem has been more and more