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[目的]探讨儿童时期甲状腺疾病的病因构成及相关因素,了解本地区儿童甲状先疾病分布特点及诊治策略。[方法]对2008年1月～2010年12月来我院就诊的93例甲状腺疾病患儿的临床资料进行分析。[结果]93例患儿中Grace’s病35例,先天性甲状腺功能低下24例;桥本氏甲状腺炎19例,单纯性甲状腺肿15例。除先天性甲低外,发病年龄多在7岁以上,且以女性为主。本组病例甲状腺肿大的主要原因为Grace’s病,甲状腺抗体在桥本氏甲状腺炎、Grave’s病均有增高。甲状腺功能对儿童生长发育有明显影响,此类疾病的就诊时机是影响此类患儿愈后的主要因素。[结论]本地区儿童甲状腺疾病以先天性及免疫性甲状腺疾病为主,单纯性甲状腺肿也较多见。进一步提高新生儿甲低筛查覆盖率,加强对学龄期儿童甲状腺疾病的关注,定期监测甲状腺功能,是早期诊断和规范治疗儿童甲状腺疾病,保证儿童正常的生长发育的关键。
[Objective] To explore the etiology and related factors of thyroid disease in childhood and to understand the distribution characteristics of thyroid pre-disease in this region and its diagnosis and treatment strategies. [Method] The clinical data of 93 cases of thyroid disease in our hospital from January 2008 to December 2010 were analyzed. [Results] Among 93 children, 35 were Grace’s disease, 24 were congenital hypothyroidism, 19 were Hashimoto’s thyroiditis and 15 were simple goiter. In addition to congenital hypothyroidism, the onset of age more than 7 years of age, and dominated by women. This group of patients with goiter is mainly due to Grace’s disease, thyroid antibodies in Hashimoto’s thyroiditis, Grave’s disease have increased. Thyroid function has a significant impact on children’s growth and development, the timing of such diseases is the main factor affecting the prognosis of such children. [Conclusion] Thyroid diseases in this area are mainly congenital and immune thyroid diseases, simple goiter is also more common. To further improve the neonatal hypothyroidism screening coverage and strengthen the attention of thyroid disease in school-age children, regular monitoring of thyroid function is the key to early diagnosis and standard treatment of children with thyroid disease, to ensure the normal growth and development of children.