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为验证大豆饮食是否能减缓雌激素诱发幼鼠前列腺癌的作用,选择动物进行实验,结果表明:①用不含大豆饲料喂养雄性成鼠,尿中雌激素样异黄酮类物质含量极微,改用含大豆饲料喂养雄鼠14天后尿中排泄的异黄酮增加20～200倍;再以不含大豆饲料喂养,尿中异黄酮很快降至原来的低水平。②对出生16天的小鼠给含大豆饲料或饲料中加入已烯雌酚(6μg/kg),喂养7天后处死,称子宫重量与体重,结果子宫相对重量较未用大豆喂养动物重10％～15％(P<0.05),给已稀雌酚(6μg/kg)喂养7天后子宫增重与对照组比较P<0.001,证明了大豆的雌激素样活性。然而,当饲料中加入大豆时,子宫对己烯雌酚的增重反应减小(P<0.001),表明大豆作为
In order to verify whether soybean diet can slow estrogen-induced prostate cancer induced by estrogen, the animals were selected for experiments. The results showed that: ①The content of estrogen-like isoflavones in urine was minimal with the diet without soybean feed Isoflavones excreted in the urine increased by 20-200 folds after 14 days of feeding the male mice with the soy-containing diet; and then fed without the soy-based diet, urinary isoflavones quickly dropped to their original low levels. (2) Diethylstilbestrol (6μg / kg) was added to the mice born on the 16th day to the feed containing soybean or diets, which were sacrificed 7 days after feeding, and the uterus weights and body weights were calculated. As a result, the relative uterine weight was 10% ~ 15% (P <0.05). The uterus weight gain after 6 days feeding of diluted estrogen (6μg / kg) was P <0.001 compared with the control group, which proved the estrogenic activity of soybean. However, when soybean was added to the diet, the uterus reduced the weight gain of diethylstilbestrol (P <0.001), indicating that soybeans as