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目的研究伊白沙坦治疗原发性高血压的临床疗效,观察对脂质和血糖的影响。方法80例原发性高血压患者,随机分为治疗组和对照组,治疗组采用伊白沙坦治疗,对照组采用硝苯地平治疗,疗程均为4周。结果治疗组显效32例(82.5%),有效5例(12.5%),总有效率为95%。对照组显效22例(55%),有效10例(25%),总有效率为80%。两组差异显著(P<0.05),两组降压幅度比较差异无显著性(P>0.05),两组对血糖、脂质的影响差异无显著性(P>0.05)。结论伊白沙坦能明显降低血压而对血糖、血脂无不良影响。
Objective To study the clinical efficacy of ibupartan in the treatment of essential hypertension and observe the effects on lipid and blood glucose. Methods Eighty patients with essential hypertension were randomly divided into treatment group and control group. The treatment group was treated with ibuprofen, while the control group was treated with nifedipine for 4 weeks. Results The treatment group 32 cases (82.5%), effective in 5 cases (12.5%), the total effective rate was 95%. The control group markedly effective in 22 cases (55%), effective in 10 cases (25%), the total effective rate was 80%. There was no significant difference between the two groups (P <0.05). There was no significant difference between the two groups (P> 0.05). There was no significant difference in blood glucose and lipid between the two groups (P> 0.05). Conclusion Irbesartan can significantly lower blood pressure without adverse effects on blood glucose and blood lipids.