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据外讯报道,一九八一年夏天美国罗契斯特大学Ro-chester大学哈佛大学等三个研究小组分别成功地对疗效显著的抗癌剂阿克拉霉素A的非糖成分的结构作出了解释,并成功地合成了阿克拉菌素酮。有关人士认为,这项成功具有很大意义。 阿克拉霉素A属于正定霉素(柔红霉素)和阿霉素等常用的蒽环型药物(系)。由于蒽环型药毒性强(尤其对心脏)所以用来治疗急性白血病等癌症,很不理想。
According to foreign news reports, in the summer of 1981, three research groups, Rohstoff University, Harvard University, at the University of Rochester, respectively successfully made the structure of the non-sugar component of aclacinomycin A, a significant anti-cancer agent, Explained, and the successful synthesis of acterin ketone. Concerned people think that this success is of great significance. Aclacinomycin A belongs to the commonly used anthracyclines such as daunomycin and doxorubicin. As anthracycline drug toxicity (especially for the heart) so it is used to treat cancer such as acute leukemia, is not ideal.