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ECT的治疗作用至少在抑郁症是与其抽搐发作有关,而与引起发作的电流无关。然而,ECT所引起的记忆障碍及其他器质性表现则与电刺激直接有关。ECT时以出现全身强直性痉挛发作疗效最好,阈下刺激引起的顿挫性发作或局灶性发作疗效比大发作差。但增加电量并不增加疗效,相反电量过大器质性遗忘会因而增加。因此治疗时应采用足以引起一次全面发作的最小电量。我们认为短促脉冲刺激比正弦波刺激为好。同时可使用非优势半球单侧电极,以减少言语记忆功能障碍。ECT的适应症最常是内源性抑郁和符合DSM-Ⅲ诊断标准的伴有忧郁的重性抑郁
The therapeutic effect of ECT, at least in depression, is related to its convulsive seizures, regardless of the current causing the seizure. However, ECT-induced memory impairment and other organic manifestations are directly related to electrical stimulation. ECT when the onset of tonic spasms have the best effect, subthreshold stimuli caused by the onset of pounding or focal attack worse than the worse. However, increased power does not increase the efficacy of the contrary, excess power will lead to increased organic forgetting. Therefore, the treatment should be used to cause a full-blown minimum power. We think short pulse stimulation is better than sine wave stimulation. At the same time can use the non-dominant hemisphere unilateral electrodes to reduce speech memory dysfunction. ECT indications are most often endogenous depression and DSM-Ⅲ diagnostic criteria associated with melancholic major depression