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目的探讨发生异位妊娠(EP)的相关危险因素,提出预防措施。方法采用病例对照法,将遂平县人民医院收治的EP孕妇130例作为研究组,选择同期行人工流产或药物流产的健康妊娠妇女130例作为对照。收集两组患者的相关信息,包括患者的一般情况、婚育史、妇科疾病史、腹部手术史等,对可能影响EP的因素进行单因素和多因素Logistic回归分析。结果单因素分析结果显示盆腔炎史、流产史、既往分娩史、不孕史、腹部手术史、EP史、IUD使用是EP发病的危险因素(P<0.05)。多因素分析筛选出4个主要危险因素,即流产史(OR=3.698)、腹部手术史(OR=3.471)、IUD使用(OR=3.207)、盆腔炎史(OR=2.706)。结论 EP与多种因素有关,积极采取相应预防措施,对降低EP的发病率有积极作用。
Objective To investigate the related risk factors of ectopic pregnancy (EP) and to propose preventive measures. Methods 130 cases of EP pregnant women treated in Suiping People ’s Hospital were selected as the study group by case control method. 130 healthy pregnant women who underwent induced abortion or medical abortion were selected as the control group. Collecting information about two groups of patients, including the general situation of patients, the history of marriage and childbirth, the history of gynecological diseases and the history of abdominal surgery. Univariate and multivariate logistic regression analysis were conducted on the factors that may affect the EP. Results The results of univariate analysis showed that the history of pelvic inflammatory disease, abortion history, previous delivery history, infertility history, abdominal surgery history, EP history and IUD use were the risk factors of EP (P <0.05). Multivariate analysis screened four major risk factors: history of abortion (OR = 3.698), history of abdominal surgery (OR = 3.471), IUD use (OR = 3.207) and history of pelvic inflammatory disease (OR = 2.706). Conclusions EP is related to many factors and actively take corresponding preventive measures, which has a positive effect on reducing the incidence of EP.