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目的:观察自拟健脾益胃化瘀方治疗胃癌前病变(PLGC)的临床疗效。方法:将120例PLGC患者随机分为两组。治疗组60例予健脾益胃化瘀方并随证加减,每日2次;对照组60例予常规西医治疗,Hp阳性加阿莫西林、克拉霉素、枸橼酸铋钾口服;胃黏膜萎缩、胃酸减少加维生素C;溃疡加奥美拉唑,两组疗程均为3个月,观察证候疗效、胃镜、病理检查。结果:治疗组总有效率为95.0%,对照组为81.7%,两组比较差异有统计学意义(P<0.05)。结论:健脾益胃化瘀方治疗胃癌前病变疗效肯定。
Objective: To observe the clinical efficacy of Jianpi Yiwei Huayu Recipe in treating gastric precancerous lesions (PLGC). Methods: 120 PLGC patients were randomly divided into two groups. Sixty cases in the treatment group were given Jianpi Yiwei Huayu Decoction and were treated twice a day with 60 cases in the control group. Western medicine treatment was given in the control group, with Hp plus amoxicillin, clarithromycin and bismuth potassium citrate orally. Gastric mucosal atrophy, gastric acid reduction plus vitamin C; ulcer plus omeprazole, two courses of treatment were 3 months, observe the efficacy of the syndrome, endoscopy, pathological examination. Results: The total effective rate was 95.0% in the treatment group and 81.7% in the control group, with significant difference between the two groups (P <0.05). Conclusion: Jianpi Yiwei Huayu Fang treatment of gastric precancerous lesions with certain effect.